Search results for "Salt solution"

showing 7 items of 7 documents

Elucidation of reaction process between solid tricalcium silicate and a lanthanum salt solution in connection with the precipitation pH. Extension to…

1993

Abstract Dissolution of tricalcium silicate is strongly accelerated in a La salt solution and releases the amounts of OH, Ca and silicate ions just required to precipitate all of lanthanum at pH 8. It remained to be proved that (1) La silicate hydrate could form at pH 8, and (2) Ca silicate hydrate could not precipitate simultaneously. The plot of silicate hydrate and hydroxide precipitation pH of La, Ca and other elements (Th, Zr) against the dropped volume of K2SiO3 and KOH solution and some physico-chemical characterization methods bring affirmative answers to these questions and allow the immobilization process of La and other elements in the presence of tricalcium silicate to be better…

Precipitation (chemistry)Inorganic chemistrychemistry.chemical_elementGeneral ChemistryCondensed Matter PhysicsSilicatechemistry.chemical_compoundSalt solutionchemistryScientific methodLanthanumHydroxideGeneral Materials ScienceHydrateDissolutionSolid State Ionics
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Solutions properties and solute–solvent interactions in ternary sugar–salt–water solutions

2010

International audience; Viscometric constants were used to provide information on solute-solvent interactions in ternary water-sugar-salt solutions. Comparison was made between pure water and aqueous salt solution as solvents affecting the behaviour of small carbohydrates. The determination of intrinsic viscosity was made more accurate by applying triple extrapolation of the three equations (Huggins. Kramer and Meffroy-Biget). Results obtained with this triple extrapolation method were compared to that obtained with the Jones-Dole equation usually used. The B coefficient of the Jones-Dole equation was interpreted in terms of its components (B(size)) and (B(structure)), respectively assigned…

Intrinsic viscositySalt (chemistry)Thermodynamicsinteraction02 engineering and technologyFood chemistry010402 general chemistry01 natural sciencesAnalytical ChemistryViscosityMolar volume020401 chemical engineering[SDV.IDA]Life Sciences [q-bio]/Food engineering0204 chemical engineeringaqueous salt solutionsapparent molar volumechemistry.chemical_classificationAqueous solutionChromatographyGeneral Medicine6. Clean water0104 chemical sciencesSolventchemistrysugarsviscosityTernary operationhydrationFood Science
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Polyoxypregnanes as safe, potent, and specific ABCB1-inhibitory pro-drugs to overcome multidrug resistance in cancer chemotherapy in vitro and in vivo

2021

Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no ABCB1-inhibitory drugs have been approved to treat MDR cancer clinically, mainly due to the inhibitor specificity, toxicity, and drug interactions. Here, we reported that three polyoxypregnanes (POPs) as the most abundant constituents of Marsdenia tenacissima (M. tenacissima) were novel ABCB1-modulatory pro-drugs, which underwent intestinal microbiota-mediated biotransformation in vivo to generate active metabolites. The metabolites at non-toxic concentrations restored chemosensitivity in ABCB1-overexpressing cancer cells v…

ABCC1 ATP binding cassette subfamily C member 1IC50 half maximal inhibitory concentrationMultidrug resistancePharmacologyNADPH reduced nicotinamide adenine dinucleotide phosphateF bioavailabilitychemistry.chemical_compoundPCR polymerase chain reaction0302 clinical medicineMDR multidrug resistanceECL electrochemiluminescencet1/2 elimination half-lifeLC–MS liquid chromatography coupled with mass spectrometryN.D. not detectedGeneral Pharmacology Toxicology and PharmaceuticsBBB blood–brain barriermedia_commonATF3 activating transcription factor 30303 health sciencesChemistryABC ATP-binding cassetteNMPA National Medical Products AdministrationPXR pregnane X receptorSDS-PAGE sodium dodecyl sulfate-polyacrylamide gel electrophoresisHBSS Hankʹs balanced salt solutionABCB1Combination chemotherapyProdrugMarsdenia tenacissimaCmax peak concentrationPaclitaxelGAPDH glyceraldehyde-3-phosphate dehydrogenase030220 oncology & carcinogenesisBHI brain heart infusionOriginal ArticleAUC0–∞ area under plasma concentration vs. time curveMRT mean residence timeDrugmedia_common.quotation_subjectRM1-950Vd volume of distributionABCB1 ATP binding cassette subfamily B member 1UIC-2 mouse monoclonal ABCB1 antibodyABCG2 ATP binding cassette subfamily G member 2Combination chemotherapyCYP cytochrome P450 isozymePI propidium iodideTEER transepithelial electrical resistance03 medical and health sciencesPBS phosphate buffer salineFBS fetal bovine serumDox doxorubicinIn vivoPOP polyoxypregnanemedicine030304 developmental biologyEVOM epithelial tissue voltohmmeterTmax time for peak concentrationCancerLBE lowest binding energyPE phycoerythrinmedicine.diseaseMultiple drug resistancePolyoxypregnanePapp apparent permeabilityN.A. not applicableCancer cellH&E hematoxylin and eosinMDR1a multidrug resistance protein 1aTherapeutics. PharmacologyqPCR quantitative PCRM. tenacissima Marsdenia tenacissimaCL clearanceSD standard derivationActa Pharmaceutica Sinica B
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Elastic properties of DNA linked flexible magnetic filaments.

2011

Elastic properties of magnetic filaments linked by DNA in solutions of univalent and bivalent salts with different pH values are investigated through their deformation in an external field. A strong dependence of the bending modulus in bivalent salt solution on the pH is shown. Experimental results are interpreted on the basis of the magnetic elastica.

Quantitative Biology::BiomoleculesChemistryFlexural modulusQuantitative Biology::Molecular NetworksCondensed Matter PhysicsBivalent (genetics)Salt solutionchemistry.chemical_compoundCrystallographyChemical physicsExternal fieldGeneral Materials ScienceElasticity (economics)DNAJournal of physics. Condensed matter : an Institute of Physics journal
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How to apply the Kirkwood–Buff theory to individual species in salt solutions

2013

It is generally assumed that the Kirkwood–Buff (KB) theory cannot be applied to anions and cations individually in a solution, as one cannot simulate this system in an open ensemble due to the electroneutrality constraint. By applying our recently derived KB theory for closed systems, we show that one does have access to single-ion properties in Molecular Dynamics. Our findings are supported by simulations for a model of a salt solution in which particles interact with WCA potentials, as well as for the NaCl/water system using the Particle Mesh Ewald technique for electrostatics.

Constraint (information theory)chemistry.chemical_classificationMolecular dynamicsSalt solutionchemistryComputational chemistryParticle MeshGeneral Physics and AstronomySalt (chemistry)ThermodynamicsPhysical and Theoretical ChemistryElectrostaticsChemical Physics Letters
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Effects of ions on water structure: a low-field (1) H T1 NMR relaxometry approach

2014

Aqueous salt solutions play an important role in nature because of their effects on environmental biogeochemical processes and on structural properties of biomolecules. Upon dissolution, salts split in ions that are solvated. Water in hydration shells is subjected to molecular motions that can be monitored by (1) H T1 NMR relaxometry. This technique allowed the evaluation of the nature of the interactions between water and ions via variable temperature experiments. Examination of relaxometry properties of aqueous solutions at variable salt concentrations allowed acknowledgement of the role played by ions in either structuring or destructuring water aggregates. A mathematical model has been …

T1kosmotrope1Hrelaxometrywaterfast field cyclingchaotropesalt solution1H; NMR; T1; chaotrope; fast field cycling; kosmotrope; relaxometry; salt solution; waterNMR
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Effects of intraocular cefotaxime on the human corneal endothelium

2001

Abstract Purpose To ascertain whether 0.4 mL of cefotaxime 0.25% applied intracamerally causes toxic alteration of the human corneal endothelium. Methods In this prospective randomized masked study, 66 patients had cataract extraction using phacoemulsification, a frown incision, and implantation of a poly(methyl methacrylate) intraocular lens. This was followed by intraocular injection of 0.4 mL of cefotaxime 0.25% or balanced salt solution (BSS®). Contact specular microscopy and photography were performed preoperatively and 1 to 4 days and 3 months postoperatively. Results In the cefotaxime group, the mean endothelial cell count was 2729 cells/mm 2 ± 474 (SD) preoperatively, 2520 ± 462 cel…

AdultMalemedicine.medical_specialtyCorneal endotheliumCefotaximeAnterior Chambermedicine.medical_treatmentCell CountIntraocular lensBalanced salt solutionCefotaximeDouble-Blind MethodLens Implantation IntraocularCorneaOphthalmologymedicineHumansProspective StudiesAgedCell SizeAntibacterial agentAged 80 and overEndophthalmitisPhacoemulsificationbusiness.industryEndothelium CornealPhacoemulsificationMiddle AgedSensory SystemsCephalosporinsEndothelial stem cellOphthalmologymedicine.anatomical_structureFemaleSurgerysense organsbusinessmedicine.drugJournal of Cataract and Refractive Surgery
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